| - | - | - |
|---|---|---|
| Product Group | : | Vitamins and Minerals |
| Pharmaceutical Form | : | Emulsion for Injection |
| Active Ingredient | : | Vitamin E, Sodium Selenite, Vitamin B1 |
| Target Animal | : | Cattle, Horse, Sheep, Goat, Dog, Cat |
| Package Form | : | 20 ml, 50 ml and 100 ml Amber Colored Glass Flacons |
COMPOSITION
It is a white colored, ready-to-use, sterile solution containing 1 mg Sodium selenite, 60 mg Vitamin E and 40 mg Vitamin B1 per ml.
PHARMACOLOGICAL PROPERTIES
Selenium is one of the essential trace elements required by the body. It is necessary for normal growth and reproduction. It is used in the prevention and treatment of many degenerative diseases in domestic animals. Its effects are similar to those of vitamin E in many ways. The two substances complement each other's effects. Vitamin E has biological antioxidant properties. Vitamin B1 promotes normal development, regulates digestion and absorption, and acts as a coenzyme in carbohydrate metabolism. It has a preventive effect on functional disorders in the nervous system. Since selenium and vitamin E must be obtained in certain amounts from the diet, their deficiencies are important for all domestic animals. E-sevil Emulsion for Injection is a medication formulated to prevent and treat disorders arising from these deficiencies.
AREA OF USE/INDICATIONS
E-sevil Emulsion for Injection is used in young animals, especially calves, for the treatment of white muscle disease, known as nutritional muscle dystrophy, in the prevention of deficiency syndromes in offspring born to pregnant animals fed a diet deficient in selenium and vitamin E, in cases of weakness and atrophy resulting from nutritional deficiency in the muscles, convulsions, paralysis, transport stress, decreased appetite, liver necrosis, infertility due to the absence or deficiency of active ingredients in the formulation, and developmental disorders in young animals.
In horses: Myoglobinuria and myositis.
USAGE AND DOSAGE
It is administered subcutaneously and intramuscularly in pregnant cow, horse, sheep, goat-lamb, kid, calve, foal, cat and dog.
Dose table; Prevention Treatment
Cow, Horse (from 5. Months of pregnancy) 5-10 ml ----
Sheep, Goat (from 3. Months of pregnancy) 1-2 ml ----
Calve, foal 0,5-1 ml 1-2 ml
Lamb, kid (1-7 days old) 0,25 ml 0,25-0,5 ml
Lamb, kid (7-30 days old) 0,25-0,50 ml 0,5-1 ml
Lamb, kid (bigger than 1 month old) 0,5-1 ml 1-2 ml
Cat and Dog --- 0,1-1 ml
If needed, the dose can be repeated one week later.
Shake well before use.
In continuous treatment, maximum 4 doses can be administered in 2 week intervals.
SPECIAL CLINICAL INFORMATION AND SPECIAL WARNINGS FOR TARGET SPECIES
Some animals may have sensitivity to selenium and thus, a test dose should be performed before administration. In sensitive animals, half dose can be administered in consecutive two days. As selenium is a toxic substance, therapeutic doses should not be exceeded. Horses are sensitive to selenium.
ADVERSE EFFECTS
Hypersensitivity is rarely observed in cattle. In such cases, symptomatic treatment should be
administered. A temporary irritation may occur in injection site.
DRUG INTERACTIONS
There is no incompatiblity with other products.
SYMPTOMS OF OVERDOSE, PRECAUTIONS AND ANTIDOTE
If high doses are administered, increase in number of breaths, dyspnea, tachycardia, diarrhea, behavioral disorders and collapse may be observed. Symptomatic treatment is applied for overdose cases. There is no specific antidote.
WITHDRAWAL PERIODS
‘0’ day for meat and milk.
CONTRAINDICATIONS
There is no any contraindications.
GENERAL WARNINGS
Consult a veterinarian before use and if any unexpected effects occur. Keep out of reach of children.
PRECAUTIONS TO BE TAKEN BY THE ADMINISTRATOR AND WARNINGS FOR VETERINARY SURGEON
Avoid contact with the product. Wash your hands after use.
STORAGE CONDITIONS AND SHELF LIFE
It should be stored in the original packages, protected from light, and below 25°C, without being placed in the refrigerator or freezer. The shelf life is 3 years.
COMMERCIAL PRESENTATION FORM
20 ml, 50 ml and 100 ml amber colored glass vials with box.
PLACE AND CONDITIONS OF SALE
It is sold in pharmacies and veterinary clinics with a veterinarian’s prescription. (VHP)
APPROVAL DATE OF LEAFLET: 12.04.2013
MARKETING AUTHORIZATION DATE AND NO: 26.03.1999-009/0849
NAME AND ADDRESS OF MARKETING AUTHORIZATION HOLDER
VİLSAN Veteriner İlaçları Tic. Ve San. A.Ş.
Balıkhisar Mah. Balıkhisar Köyiçi Küme Evleri No:765A Akyurt/Ankara/Turkiye
MANUFACTURER COMPANY
VİLSAN Veteriner İlaçları Tic. Ve San. A.Ş.
Balıkhisar Mah. Balıkhisar Köyiçi Küme Evleri No:765A Akyurt/Ankara/Turkiye
Made in Turkiye
